http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2196126-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_edd27adc0bd3e21444da30f49bed7468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11762011fdb241a356d85f83ac477e71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd5f6a8cf4cbb0c62566846e2b64bd78 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C22-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-16 |
| filingDate | 2001-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcbb4e22aadb245c9763f7506160edd3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1946986ddf7bd9a052da105ab147d74e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46a2218b9e827597423dc846527d7d27 |
| publicationDate | 2003-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2196126-C1 |
| titleOfInvention | Method of synthesis of benzhydryl chlorides |
| abstract | FIELD: chemical-pharmaceutical industry, organic chemistry, chemical technology. SUBSTANCE: invention relates to synthesis of benzhydryl chloride that is a semifinished article used in synthesis of medicinal preparations cinnarizine, cetirizine, hydroxyzine. Benzhydryl chloride of the formula where X means H or Cl is synthesized by interaction of benzhydrols of the formula where X has the above given values with concentrated hydrochloric acid in the mole ratio corresponding benzhydrol : hydrochloric acid = 1 : (2.5-8), respectively, in the presence of water-soluble organic solvent, in part, acetone or dioxane being acetone or dioxane are used in the amount 1-2 vol. p. per 1 weight p. of corresponding benzhydrol. EFFECT: increased yield and enhanced purity of end compound. 2 cl, 5 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112723986-A |
| priorityDate | 2001-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.