| abstract |
FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to nitrogen-containing heterocyclic compounds of the formula (I) or their pharmaceutically acceptable salts or isomers where m = 0 or 1; n = 0; R 1 means hydrogen atom, benzyl group, (C 1 -C 2 --alkyl)-(C 6 -C 10 -aryl), heteroaryl-C 1-2 --alkyl; A means group of the formula or where R 6 , R 7 , R 8 , R 9 mean C 1 -C 6 --alkyl; Z 1 and Z 2 mean hydrogen atom; B presents C 6 -C 10 --aryl that can be substituted with CH 3 or OH. Compounds of the formula (I) show analgetic activity and can be used in medicine. EFFECT: improved method of synthesis, valuable medicinal properties. 10 cl, 1 tbl, 18 ex |