| abstract |
FIELD: medicine, oncourology. SUBSTANCE: it is suggested to conduct polychemotherapy course in pre- operational period according to the scheme: the 1st day - vincristine 1.4 mg/m 2 intravenously by jet injection; the 2nd day - 150 ml autoblood is supplemented with 70 mg/m 2 adriamycin, the mixture is incubated for 30 min, reinfused intravenously by drops; the 4th day - 500 mg depot-prover is injected intramuscularly; 7-10 days later it is conducted a radical nephrectomy, and 7-10 days after operation it is necessary to repeat the above-described polychemotherapy, autohemotherapy and introduction of depot-prover. The method provides to decrease toxic manifestations, complications of hormonal nature, increase relapse-free period and decrease the possibility for metastasis. EFFECT: higher efficiency of therapy. 2 ex |