| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57f61d3be02f3c4fec1a0743538c6e72 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-212 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 |
| filingDate |
1995-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_301725b2eb543d4a4c04b46d5f6c2a89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea3ce2de88842dd77f1de7664d6e3c2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bf84f56d1f0f190d7a6bce40b48a897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49e4118ebe33c3f83acb26c5b5e2ed9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c13e996c2074e782fff780ae3ac58dbb |
| publicationDate |
2002-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2186582-C2 |
| titleOfInvention |
Method of isolation and purification of protein of moraxella catarrhalis external membrane, strain moraxella catarrhalis for preparing protein cd, isolated and purified nondenaturated protein cd of moraxella catarrhalis external membrane and immunogenic composition comprising protein cd of moraxella catarrhalis external membrane |
| abstract |
FIELD: immunology, biochemistry. SUBSTANCE: protein is isolated from bacterial strain Moraxella catarrhalis, cellular lysate obtained by disruption of cellular mass of bacterial strain is fractionated by centrifugation for preparing precipitate and supernatant. Precipitate is extracted selectively to remove residual soluble proteins, membrane proteins and other proteins differing from protein CD and other contaminating impurities. The remaining CD-containing precipitate is dispersed, solubilized and then fractionated by centrifugation to remove cellular residue. The strain Moraxella catarrhalis RH 408 is used for preparing protein CD of external membrane. Protein CD is used in immunogenic compositions, in part, for administration to patient in vivo. Invention ensures to develop the protection against diseases caused by bacterial pathogen which produces protein CD or protein that is able to induce antibodies in recipient and showing specific reaction with protein CD. EFFECT: improved method of isolation and purification of protein, valuable medicinal properties. 15 cl, 8 dwg, 1 tbl, 8 ex |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2601158-C1 |
| priorityDate |
1994-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |