http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2183212-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0abcd5a5a997bc09b60f855620d4e870 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02W30-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C05G5-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C05G3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N57-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C05F11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C05F11-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N41-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N37-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N3-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C04B- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C04B24-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
| filingDate | 1996-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6e922d713b29accb177114bb4fe3dc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ec0d12703e9ca976e7b8e77deec38c5 |
| publicationDate | 2002-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2183212-C2 |
| titleOfInvention | Antibacterial cephalosporins, pharmaceutical composition based on thereof and method of treatment |
| abstract | FIELD: organic chemistry, antibiotics, pharmacy. SUBSTANCE: invention relates to novel derivatives of cephalosporin of the general formula (I) where R 1 means hydrogen atom or ester group; R 2 means the group of formulas (IIa) , (IIb) , (IIc) ; Y means hydrogen atom, substituted alkyl or acyl; R 4 means hydrogen atom, phenyl, cycloalkyl or alkyl; R 5 means hydrogen atom, phenyl, cycloalkyl, lower alkyl, saturated or unsaturated 5-6-membered heterocyclyl optionally substituted with alkyl, trifluoroalkyl, oxo- or amino-group, benzothiazolyl or the group of formulas (IId) , (IIe) , (IIf) ; R 7 means alkyl; R 8 means hydrogen atom, cycloalkyl or alkyl; R 9 means hydrogen atom or alkyl; R 10 means hydrogen atom, alkyl, substituted alkyl where a substituent is taken among trifluoroalkyl, pyridyl, hydroxy-, alkoxy-group, halogen atom, amino-group or residue of sulfonic acid; hydroxy-, amino-group, phenyl, alkenyl, cycloalkyl or the group of the formula N= CH-Phe where Phe means phenyl substituted with hydroxy-group; or R 9 and R 10 in common with nitrogen atom mean saturated, unsaturated or substituted 5-6-membered heterocyclyl comprising one or two nitrogen or oxygen atoms being a substituent is taken among formyl or alkyl and so on. The compound of the formula (IVa) where R x means the group of the formula NH- C(CH 3 ) 3 and so on; R y means NH and R z means hydrogen atom and so on. Invention relates to also to a pharmaceutical composition designated for treatment of diseases caused by microorganisms and comprising the compound of the formula (I) in the form of pharmaceutically acceptable salt or as a free form in combination with at least one pharmaceutical carrier or diluting agent. Invention relates to also a method of treatment of diseases caused by microorganisms that involves administration of effective compounds of the formula (I) in a person who needs with so treatment. EFFECT: new antibacterial cephalosporins indicated above, valuable medicinal properties. 13 cl, 4 tbl |
| priorityDate | 1995-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 207.