http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2182153-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8be6a6c990669567cc455d32b00535e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J53-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 |
| filingDate | 1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97abf447fd5ddee8e0edf85aaff7af1e |
| publicationDate | 2002-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2182153-C2 |
| titleOfInvention | Steroid compound, methods of its synthesis, pharmaceutical composition |
| abstract | FIELD: organic chemistry, steroids, pharmacy. SUBSTANCE: invention relates to steroid compound of the general formula (I) where means =O, -OH, OR or OOCR where R means alkyl group with from 1 to 6 carbon atoms; R 6 means H or where m = 1 or 2; R 7 means H, C 1-4 - alkyl, C 2-4 - alkenyl or C 2-4 - alkynyl; R 11 means H, C 1-4 - alkyl, C 2-4 - alkenyl, C 2-4 - alkynyl; E means (with exception of carbon atoms 16 and 17 of ring D) 4-7-membered hydrocarbon ring where indicated ring is at α- position with respect to ring D substituted with the group R E , and comprises optionally one endocyclic double bond; R E means H, C 1-5 alkyl, C 2-5 - alkenyl, C 2-5 - alkynyl, C 1-5 - alkylidene, -(CH 2 ) n -N 3 or -(CH 2 ) n where n = 1 or 2 and where alkyl group can be substituted for OR, -OOCR where R is alkyl with 1-6 carbon atoms; R 17 means OH, -OR or OOCR where R means alkyl with 1-6 carbon atoms where indicated steroid compound can involve but optionally a single double bond, Δ5(10), Δ4(5) either ring A can be aromatic. The invention relates to also a pharmaceutical composition comprising the indicated steroid compound. Steroid compounds of the invention shows very high effectiveness for prophylaxis or treatment of disorders associated with per- or post menopause and, more preferably, for prophylaxis or treatment of osteoporosis. Except for, steroid compounds of the invention can be used as contraceptive agents. EFFECT: improved method of synthesis, valuable medicinal properties of steroid compound. 10 cl, 1 tbl, 8 ex |
| priorityDate | 1997-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.