abstract |
FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to novel derivatives of carbamic acid of the general formula (I) where R 1 and R 2 mean independently each of other alkyl, aryl, aralkyl, heteroaryl, cycloalkyl or heterocyclyl; R 3 and R 4 means independently each of other hydrogen atom, alkyl, halogen atom, hydroxyl or aryl; R 5 means -CCO-R 6 where R 6 means hydrogen atom or alkyl; A means alkylene or alkenylene; B means -O(CH 2 ) m - or -(CH 2 ) n -; m means the whole number from 1 to 8; n means the whole number from 0 to 8, or to their racemates or individual isomers or to their novel pharmaceutically acceptable salts or solvates. Invention can be used as therapeutic medicinal agents. Invention relates to also method of synthesis of these compounds, pharmaceutical composition based on the novel derivatives of carbamic acid and method of treatment of patients with morbid state associated with intermittent lameness. EFFECT: new compounds indicated above, improved method of synthesis, valuable medicinal properties. 20 cl, 2 tbl, 25 ex _ |