http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2176915-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f108c4feccfd12a503eaaf29a1aae3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3c8c16d390c39e0d25b7e1076d2bd08 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-727 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 |
| filingDate | 1997-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5b04527c0c6fd1a509829a3a45ab077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5775da2244df8ac68816259234e754d4 |
| publicationDate | 2001-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2176915-C2 |
| titleOfInvention | Half-synthetic sulfaminoheparosansulfates having antimetatstatic activity and lowered hemorrhagic risk |
| abstract | FIELD: medicine. SUBSTANCE: preparation is composed sulfaminoheparosansulfate compounds as antimetatstatic agent and pharmaceutical composition containing them. New compounds have molecular mass of 3200-4000 and sulfate-to-carboxyl group ratio equal to 2.2-2.3. They are produced from polysaccharide K5 of Escherichia coli by means of N-deacethylation with hydrazine and following N- sulfatization with adduct of trimethylamine/sulfuric anhydride and then, O-sulfatization with adduct of pyridine/sulfuric anhydride at 0 C during 0.25-2 h. When performing O- sulfatization, adduct/polysaccharide ration is equal to 5(in equivalent proportion of SO/OH). Then, the product is sulfatized. EFFECT: enhanced effectiveness in treating cancer patients; reduced risk of hemorrhages. 3 cl, 1 tbl |
| priorityDate | 1996-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.