http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2176243-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c9c6ef5e5ad4eccee474f0480a6674b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 |
| filingDate | 2000-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fde0bd7f5683d2b5eee44e86ba64ee6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeddb1ec3c5825e6b98511b606c580f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdb702ceab9a09e475dff41fdd2e9125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27b79e718daac1d34147d59c9c249b38 |
| publicationDate | 2001-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2176243-C2 |
| titleOfInvention | Method of synthesis of indole derivative |
| abstract | FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method of synthesis of indole derivatives of the general formula (I) that are semiproducts and can be used for synthesis of pyrroloindoles and mitomycins where R 1 and R 2 mean OCH 3 ; R means Ph (Ia) or R means tert.-Br-Ph (Ib) or R means CH 3 (Ic); or R 1 and R 2 mean H; R means Ph (Id) or R means p-CH 3 (Ie) or R means p-Br-Ph (If) or R means p-Cl-Ph (Ig). Method of synthesis involves heating derivatives of 2-tosylaminoarylfurylmethane of the formula (2) in saturated solution of gaseous hydrogen chloride in ethanol at 70-78 C for 10-30 min. Method provides to synthesize compounds with yield 70-75% and to decrease resinification. EFFECT: improved method of synthesis, increased yield, enhanced quality of products. 2 tbl, 4 ex |
| priorityDate | 2000-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.