http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2175967-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7703f53673509ad5f03bcc1ef68db6c2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-66 |
filingDate | 1996-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2001-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31acc46808c0b3e36f57d796427e884b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5898fc610d947f6559618417034fae3 |
publicationDate | 2001-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2175967-C2 |
titleOfInvention | Pharmaceutical composition containing lactic acid butyrate prodrug |
abstract | FIELD: pharmacy. SUBSTANCE: invention relates to a pharmaceutical composition containing an effective amount of butyral precursor of drug of the formula (I) where A and D are taken independently among the group including hydrogen atom, carbocyclylalkoxyalkyl-group or C(1-4)-linear or branched alkyl, C(2-4)-linear or branched alkyl or alkynyl that can be substituted independently with hydroxy-group, alkoxy-group, carboxyalkyl-group, alkylamide-group and so on under condition that A and D do not mean hydrogen atom simultaneously; R means oxygen atom, NH, NC(1-5)-alkyl with linear or branched chain or NHC(2-5)-alkenyl with linear or branched chain being any of them can be substituted optionally with residue of carbocycle or heterocycle; Z means hydrogen atom, C(1-4)-alkyl with linear or branched chain, C(2-4)-alkenyl or alkynyl with linear or branched chain, carbocyclic or heterocyclic residue and so on and each stereogenic carbon atom can be in (R)- or (S)-configuration. Invention relates to also a pharmaceutically acceptable adjuvant or carrier. Proposed composition increases the level of embryonic hemoglobin or accelerates cell differentiation and can be used for treatment of patients with β-hemoglobinopathy and malignant blood diseases. EFFECT: new pharmaceutical compositions indicated above, valuable medicinal properties. 21 cl, 4 tbl, 1 dwg |
priorityDate | 1995-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 453.