| abstract |
FIELD: chemical industry. SUBSTANCE: described is method of preparing trovafloxacin by reacting 7-chloro- 1-(2,4-difluoropheny-6-fluoro-1,4- dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid with azobicyclo [3.1.0] hexyl derivative. Trovafloxacin is prepared without use and subsequent removal of protective groups on external aminogroup, thus making it possible to save time and cut down cost of synthesis. EFFECT: more efficient preparation method. 6 cl, 8 ex |