| abstract |
FIELD: organic chemistry, vitamins. SUBSTANCE: invention relates to novel retinoids of the formula (I) where the bond C 7 -C 8 is a double bond and one of R 1 and R 2 means C 1 -C 4 -alkyl and other means chlorine, bromine or iodine atom; or R 1 and R 2 in common mean C 3 -C 6 -alkylene; or the bond C 7 -C 8 is a triple bond and R 1 and R 2 in common mean C 3 -C 6 -alkylene, and their pharmaceutically acceptable salts or esters. EFFECT: new compounds indicated above. 8 cl, 6 tbl |