abstract |
FIELD: medicine. SUBSTANCE: preparation has granules containing mixture of enalapryl maleate, lactose, starch and polyvinylpyrralidone dusted with magnesium stearate and hydrocarbonate in given proportion. The method involves mixing enalapryl maleate, lactose, potato starch, moistening the mixture with polyvinylpyrralidone alcohol solution. The mixture is granulated under humid conditions with ethyl alcohol sprayed over the pseudoliquified mass. The granulated product is dried, dusted and tablets are produced. EFFECT: high quality of tablets dissociating during 1 min; provided high strength properties. 3 cl, 1 tbl |