http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2164224-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 |
| filingDate | 1996-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_036e10a547ec4b5d85a997b314eb669e |
| publicationDate | 2001-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2164224-C2 |
| titleOfInvention | Trisubstituted phenyl derivatives and pharmaceutical composition |
| abstract | FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel trisubstituted phenyl derivatives of the formula (1s) where R 1s means hydroxyl, alkyl containing 1-4 carbon atoms or alkoxyl containing 1-4 carbon atoms; R 2s means hydroxyl or alkoxyl at 5- or 6-position and containing 1-4 carbon atoms being R 1s and R 2s are not hydroxyl simultaneously; and a) W s means -CH 2 CH 2 -; R 3s means the group of the formula -COR 6s where R 6s means alkyl containing 1-4 carbon atoms, alkoxyl containing 1-4 carbon atoms or amino-group; R 4s means amino-group, alkylamino-group containing 1-4 carbon atoms, dialkylamino-group where each alkyl moiety has independently 1-4 carbon atoms, alkylcarbonylamino-group where alkyl moiety has 1-4 carbon atoms or alkoxycarbonylamino-group where alkoxyl moiety has 1-4 carbon atoms; or b) W s means -CH 2 CH 2 -, -CH 2 NH-, -CH 2 O- or -CH=CH- being nitrogen or oxygen atom is bound with ring B; R 3s and R 4s in common with ring B form the system of condensed rings of the formula (as) and (bs) where symbol _ _ _ _ means the ordinary or double bond; R 9s means hydrogen atom, alkylthio- -group containing 1-4 carbon atoms, alkyl containing 1-4 carbon atoms, amino-, diacetylamino-, alkylamino-group containing 1-4 carbon atoms, hydroxyl, alkoxyl containing 1-4 carbon atoms or mercapto-group; Y s/ means N or CR 11s where R 11s means hydrogen atom or alkoxycarbonyl where alkoxyl moiety has 1-4 carbon atoms; R 10s means hydrogen atom, alkyl containing 1-4 carbon atoms or dialkoxybenzyl where alkoxyl moieties have independently 1-4 carbon atoms; and Z means O or S and V means NH if symbol _ _ _ means ordinary bond and N if symbol _ _ _ means double bond under condition that if R 9s means hydroxyl or mercapto-group and Y s means N then compounds exist in tautomeric form of the formula (Its) where means O or S, in free form or as salt form if these forms are possible for existing. Compounds are useful for treatment of patients with proliferative and/or inflammatory disorders and cancer. EFFECT: new compounds indicated above, valuable medicinal properties. 4 cl, 52 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2449995-C2 |
| priorityDate | 1995-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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