| abstract |
FIELD: medicine. SUBSTANCE: described are new androstane steroids of formula I: wherein P 1 is oxo, α-(β- hydroxy, α-(β-)-C 1-4 alkoxy or α-(β- benzyloxy; P 2 is C 1-4 alkyl, hydroxy C 1-4 alkyl; P 3 is nonexistent or C 1-4 alkyl ; P 4 is hydrogen, oxo or hydroxy; P 5 is one two hydrogen atoms, methyl of methylene; P 6 is hydrogen, which are ligand semichemical products binding with neutroepithelial receptors. EFFECT: improved properties of the title compounds. 9 cl, 28 ex, 37 dwg, 1 tbl |