| abstract |
FIELD: pharmaceutical chemistry. SUBSTANCE: invention provides benzothiophene compounds with general formula I: (I), wherein R 1 is hydrogen, hydroxyl, C 1 -C 4 -alkoxy, benzoyloxy, C 1 -C 6 -alkanoyloxy or C 2 -C 6 - alkanesulfonyloxy; R 2 is the same as above or halogen; R 3 is 1- piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1- pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or hexamethylenimino; n = 2 or 3; and Z is oxygen or sulfur, and their pharmaceutically acceptable salts, which can be used for treatment of various states associated with postmenstrual syndrome, uterine fibroma diseases, endometritis, and proliferation of unstriped muscle cells. EFFECT: expanded therapeutic possibilities. 10 cl, 3 tbl, 60 ex |