| abstract |
FIELD: organic chemistry, medicine, neurology. SUBSTANCE: invention describes the novel derivatives of naphthylamide of the formula (I) where R 1 is halogen atom, cyano-group; R 2 is direct or branched alkyl with 1-6 carbon atoms; R 3 is unsubstituted phenyl or phenyl substituted with 1-2 substituents taken among C 1-6 -alkyl, halogen atom, C 1-6 -alkoxy- or thio-C 1-6 -alkoxy-group, 4-pyridinyl-, 3-benzoiso-thiazolyl- or 7-benzo[b]furanyl-group, and their pharmaceutically acceptable acid-additive salts. Compounds of the formula (I) are dopaminergic agents that can be used as antipsychotic drugs for treatment of psychotic patients, for example, with schizophrenia. EFFECT: new compounds indicated above, improved method of treatment, valuable medicinal properties. 4 cl, 1 tbl, 16 ex |