abstract |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes the novel acyl derivatives of azolones of the general formula (I) where values R 1 -R 6 , A, Y, Z are given in p. 1 of the invention claim, their pharmaceutically acceptable acid salts and stereochemically isomeric forms that are powerful agent against microorganism Helicobacter. Invention describes also method of their synthesis, compositions containing indicated compounds, methods of their preparing and use of these compounds as drugs. EFFECT: improved method of synthesis and preparing. 8 cl, 1 tbl |