| abstract |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of N-(aryloxyalkyl)-hetero-piperidine and heteroarylpiperazine of the formula (I) where X means -O-, -S-, -NH- or -N(R 2 )-; p = 1; Y means H, Cl, Br, F; R 2 means benzoyl; Z means -CH- or -N-; n = 2, 3, 4, 5; R means H, alkyl, alkoxyl, hydroxyl, bromine atom, alkylamino-, alkylthio-, trifluoroacetyl-, aminocarbonyl-group, -CO-alkyl, -COO-alkyl, -CO-Ph, -CH(OR 3 ); R 3 means H, lower alkyl; m = 1, 2, 3 or their pharmaceutically acceptable salts showing antipsychotic and/or analgetic activity. EFFECT: valuable pharmacological properties of compounds. 60 cl, 3 tbl, 61 ex |