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filingDate 1997-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1999-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c31c74b45d86ce572c3a4d45cc23779
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publicationDate 1999-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2142507-C1
titleOfInvention Strain of hybrid cultured cell of animal rattus norvegicus used for preparing monoclonal antibodies raised to human hepatitis a virus
abstract FIELD: biotechnology, immunology. SUBSTANCE: strain of hybrid transplanted cells IBM 612 is obtained by the fusion of rat myeloma cells 210RC. Y3-Ag1.2.3 with splenocytes LOU from rats immunized with the purified preparation of hepatitis A virus. The strain of hybrid transplanted cells IBM 612 produces monoclonal antibodies IgG 2B that interact specifically with hepatitis A virus. Monoclonal antibodies are used as reagents in diagnostic test-systems for detection of hepatitis A virus antigens and antibodies. EFFECT: strain indicated above, specific antibodies preparing. 1 tbl, 3 ex
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