| abstract |
FIELD: pharmaceutical chemistry. SUBSTANCE: compound of general formula I: (I), wherein R 1 is hydrogen atom, R 2 C 1 -C 6 -alkyl, and n=1, is prepared by interaction of compound III: (III) or its reactive derivative with amine V: (V) or its acid-addition salt followed by nitration of interaction product. Optically active thiazolidinone derivative shows excellent activity against angina pectoris. EFFECT: increased prophylactic and therapeutic effects. 17 cl, 2 tbl, 29 ex |