http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2139290-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-431 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 1994-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01107c4d258a81f4b0b34148d214a87d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6c49bdc8d4d2a03e29b598ecd40569c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81dc102f9b440969c2e6452140061954 |
| publicationDate | 1999-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2139290-C1 |
| titleOfInvention | DERIVATIVES OF 3-β-ALKENYLPENAM AND THEIR PHARMACEUTICALLY COMPATIBLE SALTS |
| abstract | FIELD: organic chemistry, antibiotics. SUBSTANCE: invention relates to new derivatives of 3-β-alkenylpenam of the general formula (I): β where one of and R 1 means R 2 , -CN, -COR 4 , halogen atom, -CH= -CH 2 R 5 or Q and other means hydrogen atom and either lower alkyl or both in common mean CHR 6 -lactam ring; γ means hydrogen atom, lower alkyl, arylalkyl, allyl or a radical splitting in vivo; R 3 means hydrogen atom, lower alkyl, lower alkoxy-, benzyl-oxy-, amino-, lower alkylamino-group or lower alkyl-lower alkoxyamino-group; R 4 means hydroxyl group, R 5 or five- or six-membered N-, S- and/or O-containing heteroaromatic ring bound through nitrogen atom; -OCONHR 7 ,-OCONH 2 means -CN or -CHO; R 6 means R 7 ; Q means five- or six-membered N-, S- and/or O-containing heteroaromatic ring and n = 0, 1 or 2, and pharmaceutically compatible salts of these compounds. These compounds show an inhibitory effect on -COCH 2 Cl-lactamase activity. Under definite conditions they can be used in combination with β-lactam antibiotic for prophylaxis and control of pathogens of diseases producing β-lactamase. EFFECT: new compounds indicated above, valuable pharmacological properties. 17 cl, 3 tbl, 27 ex |
| priorityDate | 1993-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 258.