| abstract |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of pyrone of the formula (I) where X - the group OR 1 ,NHR 1 ,CO 2 R 4 ,CH 2 R 4 or CH 2 OR 1 ; R 1 = R 4 or COR 4 ; R 2 - hydrogen atom, C 5-6 -cycloalkyl; R 5 - hydrogen atom, C 1-6 -alkyl (other values see p. 1 of the claim) which are useful as antiviral agents, for treatment of infections caused by human immunodeficiency virus or other retroviruses eliciting activity of aspartylproteases. EFFECT: antiviral activity of compounds. 8 cl, 3 tbl, 223 ex |