http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2136657-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7558e7e726fca41ae292cfc9ed5890fa |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C259-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
filingDate | 1995-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddf1b7367c99e378f38bad17fdd1e112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbec101fe1f2f086fb6892e08fd7db53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee0bef0b08c4c5ce7f7aede5e25ae074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45cf2e84e39c1f01c17b6759d8b3061 |
publicationDate | 1999-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2136657-C1 |
titleOfInvention | Derivatives of hydroxamic or carboxylic acid and pharmaceutical or veterinary composition on said |
abstract | FIELD: organic chemistry, biochemistry, pharmacy. SUBSTANCE: invention relates to derivatives of hydroxamic or carboxylic acid of the general formula (I) where X is COOH or CONHOH; R - H, methoxy, alkyl, C 2-6 -alkenyl, phenylalkyl or the group BSO n A-; n = 0 or 1; B is 5- or 6-membered heterocyclic ring containing sulfur or nitrogen as a heteroatom; A means -CH 2 -; R 2 - alkyl, phenylalkyl; R 3 - tert.-butyl, 1-benzylthio-1-methyleth-1-yl or the specific by-side chain of alanine, valine, leucine or phenylalanine; R 4 - phenyl or 5- or 6-membered heterocyclic ring containing sulfur or nitrogen as a heteroatom that can be condensed with benzene ring or 5-, 6- or 7-membered heterocyclic ring; R 5 - H or alkyl; or their salt or solvate that are inhibitors of metalloproteinases causing tissue degeneration and inhibitors of tumor necrosis factor release from cells. EFFECT: valuable biochemical properties of compounds. 6 cl, 1 tbl, 39 ex |
priorityDate | 1994-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 283.