| abstract |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivative of benzimidazole of the formula (I) where R 3 - a residue of the formula (a) where each A, B and D means CH or one or two of A, B and D means N and other are CH; R 11 - monocyclic heteroaryl taken from pyrimidine, imidazole, pyrrole, thiazole, oxadiazole, pyrazole, pyridine, furan possibly substituted with lower alkyl, amino-group, pyridyl, oxadiazolyl; one of R 6 and R 7 - hydrogen atom and other - furanyl or isoxazolyl, or its pharmaceutically acceptable salt or oxide or pharmaceutical composition on its base that provides modulation of GAOA-receptor complex of living organism central nervous system. EFFECT: valuable pharmacological properties of compound. 8 cl, 2 tbl, 45 ex |