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filingDate 1997-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2133622-C1
titleOfInvention Method of detection of antibody to hepatitis virus c nuclear protein
abstract FIELD: medicine, molecular immunology. SUBSTANCE: invention relates to the developed method for detection of antibodies to viral hepatitis C nuclear protein involving the contact of patient serum with antigen and conjugate. Synthetic peptide of the following structure is used as an antigen: NH 2 --Thr-Lys-Arg-Asn-Thr-Asn-Arg-Arg-Pro-Gln-Asp-Val-Lys-Phe- -Pro-Gly-Gly-Gly-Gln-Ile-Val-Gly-Gly-Val-Tyr-Leu-Leu-Pro-Arg- -Arg-Gly-Pro-Arg-Leu-Gly-CO-NH 2 . Monoclonal antibodies against human labeled with horse radish peroxidase are used as a conjugate. Invention provides diagnosis of hepatitis C at early stage. EFFECT: improved method of antibody detection. 8 tbl, 4 ex
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2667429-C2
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type http://data.epo.org/linked-data/def/patent/Publication

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