http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2131871-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1c80109783a6f3a25a27e07efcecd14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-80 |
| filingDate | 1997-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a1d2922cc31aadda8f51262406e6a63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf8be59e12a1bca4ecf9d7aff04b71b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f80edcc1292c569da0b2a8667c4a42b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8c5f6ccca324095b56eeaf402f1129 |
| publicationDate | 1999-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2131871-C1 |
| titleOfInvention | Method of preparing 1,3-dimethyl-4,8-dialcoxy-6-r-pyrrolo(thieno)-[c]- tropilium salts |
| abstract | FIELD: organic synthesis. SUBSTANCE: compounds of general formula I: (I) wherein Z is S, N-H, N-R (R is C 1 -C 10 -alkyl, C 1 -C 10 -alkoxy, and carbethoxy radicals); R 1 is hydrogen atom, styryl, phenyl, mono- or dihydroxyphenyl, mono- or dihydroxy-C 1 -C 10 -alkoxy, methylenedioxy, and di-C 1 -C 6 -alkylamino groups; R 2 is C 1 -C 10 =alkyl; and X is ClO 4 , HSO 4 , or Br; are prepared by heating 3,4-diacetylhexanedione (formula II: (II)) with hydrogen sulfide in acetic acid or by melting it with alkylamines, arylamines, their acetate salts, or ammonium acetate to form 2,5-dimethyl-3,4-diacetylpyrrols(thiophenes), which, in the same reactor or after intermediate isolation from reaction mixture, are brought into interaction with trialkyl-ortho-formiates and inorganic acid (to form compounds I with R 1 = H) or with aromatic aldehydes R 1 - CHO in presence of perchloric acid followed by treatment with trialkyl- ortho-formiate (to form compounds I with R 1 = styryl, or optionally substituted phenyl). Compounds I are potential biologically active compounds, which manifest high reactivity in reactions with nucleophils and can be used for production of various known and new biologically active compounds of pyrrolo(thyeno)-[C]-tropilium and azaazulene types. EFFECT: extended choice of biologically active compounds. 7 cl, 2 tbl, 21 ex |
| priorityDate | 1997-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.