Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8cf77b8e89e5fbdeaca0875e3bfbbf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e55b0731dbd67c3f18e240114e703e3 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate |
1997-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1999-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f17c93555d0fe899e4f240f71604b694 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cabd21bdcc9ad46883dab8c58ac61eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66443581f5b35caa7404e6e327d7af07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae2b8e4f1ee46d3f945ed1288fb288b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07dca5a389a222c2da6415f42bc3a8f0 |
publicationDate |
1999-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2128651-C1 |
titleOfInvention |
N-butylamide 2-anilino-6,7-dihydro-5h-pyrindine-3- carboxylic acid having anti-inflammatory activity |
abstract |
FIELD: chemical industry. SUBSTANCE: novel n-butyl- amide-2-anilino-6,7-dihydro-5H-pyrindine-3-carboxylic acid of formula I: . Compound is prepared by reacting n-butylamine 2-chloro-6,7-dihydro-5H-pyrindine-5- carboxylic acid with aniline hydrochloride in butanol C 19 H 23 N 3 O, mp 132-134 C. Compound (I) has antiinflammatory activity. Antiinflammatory activity of compound (I) in 50 ml/kg is by 1.4 times higher than that of orthophene. ZD 50 is more than 500 mg/kg. EFFECT: improved properties of the title compound. 2 ex, 1 tbl |
priorityDate |
1997-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |