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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-04
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filingDate 1997-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1999-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f17c93555d0fe899e4f240f71604b694
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publicationDate 1999-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2128651-C1
titleOfInvention N-butylamide 2-anilino-6,7-dihydro-5h-pyrindine-3- carboxylic acid having anti-inflammatory activity
abstract FIELD: chemical industry. SUBSTANCE: novel n-butyl- amide-2-anilino-6,7-dihydro-5H-pyrindine-3-carboxylic acid of formula I: . Compound is prepared by reacting n-butylamine 2-chloro-6,7-dihydro-5H-pyrindine-5- carboxylic acid with aniline hydrochloride in butanol C 19 H 23 N 3 O, mp 132-134 C. Compound (I) has antiinflammatory activity. Antiinflammatory activity of compound (I) in 50 ml/kg is by 1.4 times higher than that of orthophene. ZD 50 is more than 500 mg/kg. EFFECT: improved properties of the title compound. 2 ex, 1 tbl
priorityDate 1997-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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