abstract |
FIELD: medicine. SUBSTANCE: present invention describes maleic acid salt of 5-[4-[2-(N-methyl-N (2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione or isomeric or tantomeric form thereof and/or pharmaceutically acceptable solvate is prepared by reacting 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy] thiazolidine -2,4-dione with maleate ion source HOOC CH = CH COO - .. Compounds are more soluble in water, have good water stability and is useful for treating hyperton and cardio- vascular diseases. EFFECT: improved properties of the title compounds. 3 cl, 2 ex |