http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2127883-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3489dbfd4ce97e1f412d75dfce6f93cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86a607819dfc71863a2abf9405980338 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 1996-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38a3d26a099e4aef50774a5259ec0989 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9603dde4d1f89abf5c192cf407ea43ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_078b6dfac0de81d6ccf74d8a72dec74e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_516d1f796860b0ab251b7e49b6fc3948 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99683fc40c8379d8233cd900979247e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e4fb6ce79fed673246eb828e95e6840 |
| publicationDate | 1999-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2127883-C1 |
| titleOfInvention | Method of an express-diagnosis of diphtherial infection |
| abstract | FIELD: medicine, diagnosis of infection diseases. SUBSTANCE: method involves detection of diphtherial toxin by immuno-enzyme analysis using monoclonal antibodies. Reaction is carried on mouth-throat mucosa epitheliocytes that are washed out preliminary with phosphate-saline buffer, pH = 7.2-7.4, in combination with Tween-20. Mouth-throat mucosa bioptate is applied by endoscope brush on glass, fixed in 15-20% sucrose and phosphate-saline buffer solution (pH = 7.2-7.4) with 1% bovine serum albumin solution. Then monoclonal antibodies raised to COOH-terminal site of B-fragment of toxin molecule are applied followed by application of polyclonal antibodies with peroxidase and substrate mixture. Infection is diagnosed in the case of precipitation of antibodies of red-brown color. Method can be used for early diagnosis of infectious diseases. EFFECT: accelerated and simplified method, enhanced sensitivity of diphtherial toxin detection. 1 tbl, 2 ex |
| priorityDate | 1996-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.