| abstract |
FIELD: organic chemistry, heterocyclic compounds. SUBSTANCE: invention relates to heteroaryl-derivatives of the formula (I) where X means -O-, -S-, ; R 2 - lower alkyl, aryl(lower alkyl), aryl, cycloalkyl, aroyl, alkanoyl or phenylsulfonyl; p = 1 or 2; Y means hydrogen, lower alkyl, hydroxyl, chlorine, fluorine, bromide, iodine atom, alkoxy-, trifluoromethyl-, nitro- or amino-group when p = 1; or Y means lower alkoxy, hydroxyl or halogen when p = 2 and X means -O-; Q means a residue of the formulas (a) and (b) ; Z means -CH- or ; Y 2 means a residue of the formula (c) and values of other radical are given in p. 1 of an invention claim. Compounds of the formula (I) show antipsychotic activity. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 99 cl, 2 tbl, 161 ex |