abstract |
FIELD: organic chemistry and technology, pharmacy. SUBSTANCE: invention relates to derivatives of quinazoline of the formula (I) where radical values are indicated in p. 1 of an invention. Synthesized compounds show capability to inhibit tyrosine kinase receptors. EFFECT: improved method of synthesis, enhanced effectiveness of compounds synthesized. 11 cl, 1 dwg, 1 tbl, 81 ex |