| abstract |
FIELD: antineoplastics. SUBSTANCE: method is based on introducing an active curing compound, such as 5-substituted uracil, which, in hepatic cells, is converted by aldehydoxidase into bioactive diketo-containing drug or metabolite. Drug precursors are shown to be as effective in treating diseases as the drugs themselves and, at the same time, they have benefit effects and are devoid of many unfavorable effects. EFFECT: extended resource of antitumor drugs. 16 cl, 9 dwg, 4 tbl, 12 ex |