| abstract |
FIELD: organic chemistry. SUBSTANCE: invention relates to new derivatives of benzofuranylalkane carboxylic acid of the general formula (I): where R 1 - a group of the formula OR 3 where R 3 - cycloalkyl, 6-membered saturated heterocycle; R 2 - free or substituted phenyl; V - alkylene chain; W - tetrazolyl, group COR 6 or CONR 7 R 8 where R 6 R 7 ,R 8 - alkyl, cycloalkyl, phenyl, hydrogen. Synthesized compounds show antiinflammatory activity and can be used as drugs for treatment of patients with acute and chronic inflammatory processes. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 3 cl, 20 tbl, 290 ex |