| abstract |
FIELD: pharmaceutical industry. SUBSTANCE: present invention describes novel binaromatic acetylene, compounds with adamantyl group of formula (I): wherein R 1 is H, -CH 2 -O-H-,-CH 2 -O-CO-CH 3 ,, OH, -O-(CH 2 )-(CO) n -Het, -CH 2 ) p -CO-H, (CH 2 ) p CO-CH 3 ,, -CH 2 ) p CONH 2 , Het is heterocycle; Ar is substituted or unsubstituted pyridyl, phenyl, naphthalyl; R 2 is H, -O-CH 2 -O-CH 2 -CH 2 -OCH 3 ; -OR 12 straight or branched alkyl containing 1-20 carbon atoms; R 3 is -O-CH 2 -O-CH 2 -CH 2 -OCH 3 ; m is 1 or 2; n is 0 or 1; p is 0 or 1; and X is H. The present invention also describes pharmaceutical or cosmetic compositions containing effective amount of compound (I) as active ingredient, and pharmaceutical or cosmetic additives. EFFECT: improved properties of the pharmaceutical and cosmetic compositions. 16 cl, 1 tbl |