| abstract |
FIELD: organic chemistry. SUBSTANCE: invention proposes a new agent of the formula (I): where R 1 and R 3 mean independently hydrogen, CH 3 , where Ar means optionally substituted phenyl; R 2 is taken from a group consisting of pyrrolidino-, hexamethyleneimino- or piperidino-group, or its pharmaceutically acceptable salts or solvates. Synthesized compounds enhance an expression of thrombomoduline by inhibition thrombotic disorder. EFFECT: improved method of synthesis, enhanced effectiveness of compounds, broadened pattern of agents. 4 cl |