| abstract |
FIELD: medicine. SUBSTANCE: present invention describes novel compounds of formula Ia or Ic: wherein X is hydrogen or halogen; Y is hydrogen or amino group; Z is carboxy; Q is nitrogen or group of formula: wherein R 2 is hydrogen, halogen, lower alkoxy or lower alkoxy substituted by one or more halogen atoms; T is methylene group optionally substituted by lower alkyl; R 1 is hydrogen, lower alkylene, lower alkynyl, amino group optionally substituted by one lower alkyl, (C 3 -C 6 )-cycloalkyl; lower alkoxy, phenyl optionally substituted by one halogen; lower alkyl; R is group (h) or (i). The claimed compounds have anti activity. EFFECT: improved properties of the title compounds. 22 cl, 5 dwg, 110 ex, 31 tbl |