http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2120941-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_513a6f008694c228e4ce5173e00eb5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 1994-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_939cb87cf101c34005ab566293a23440 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e74256c68930782e0d3daa5bcbf2f5a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e110be0fa344ecedbc06bb03f94aab93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ae41b769b30191a65f3e1ace33e7d89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc6ad32252fc79b5963589561083e7cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1210a41a88a4ba205479743cdcf306ef |
| publicationDate | 1998-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2120941-C1 |
| titleOfInvention | Derivatives of quinolone carboxylic acid or their pharmaceutically acceptable salt |
| abstract | FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to new derivatives of quinolone carboxylic acid of the formula (I) , their pharmaceutically acceptable salts and hydrates where X means hydrocarbon group, fluorocarbon group or nitrogen atom; Y means hydrogen atom or methyl group; R 1 means hydrogen atom or C 1 -C 5 -alkyl group; R 2 means a group of the formula (a) where A and B mean fluorocarbon group or nitrogen atom at condition that when A is CF then B is N and when A is N then B is CF; R 3 means a group of the formula (b) where substitute R 4 means amino-group with racemate or (S)-enantiomer formation, or a group of the formula (c) where substituents R 5 , R 6 and R 7 mean hydrogen atom or C 1 -C 3 -alkyl group. Derivative of quinolone carboxylic acid of the formula (I) is synthesized by condensation of compound of the formula (II) and compound of the formula HR 3 in solvent in the presence of acid acceptor and excess of compound of the formula HR 3 that is one of reagents. Solvent is taken from a group involving pyridine, acetonitrile, N,N-dimethylformamide. In compound of the formula (II) and compound of the formula HR 3 substituents X, Y, Z, R 1 , R 2 and R 3 mean values indicated above. EFFECT: improved method of synthesis. 11 cl, 6 tbl, 29 ex |
| priorityDate | 1993-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 205.