| abstract |
FIELD: pharmaceutical industry. SUBSTANCE: invention describes pharmaceutical composition having antilipidemic and antiatherosclerotic activities and method of treatment of hyperlipidemia and atherosclerosis in the amount of 200-1000 mg of 1-3 grams daily. Compounds are prepared from ω-pyridylalkyl-, alkenyl-or alkynyl alcohols and 3,5-ditert-butyl-4-hydroxy-benzyl alcohol in the form of acetate thereof. In compound of formula I:(CH 2 ) n 3-Per is 3-pyridyl; m is 1, n is 4-7 or m is 3 and n is 1-7 and where bond between two carbon atoms of fragment adjacent with pyridine ring is single, double or triple. The present invention also describes pharmaceutically acceptable acid addition salts of said compounds. EFFECT: improved properties. 2 cl, 9 ex, 6 tbl |