http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2115653-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e404b57297e1d7ddf9ef360d5b19dc7 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F3-06 |
filingDate | 1995-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1998-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_729ecbed1f71d0d12ad0210cd206ebc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_988eb2e33a1a2a850a53614462c577e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54bb85b99d6c67294ee91c7fbed73893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db83ce38c67f8ebc69c8993bd7f15bc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec06a2fc8af834ea7499da1508e12390 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f779ce314fa7d6f5fe37a4a9b61f147c |
publicationDate | 1998-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2115653-C1 |
titleOfInvention | Complex substituted imidazole compounds having antidote and antihypoxanthic activities |
abstract | FIELD: medicine. SUBSTANCE: present invention describes novel compounds, namely 1-vinyl- and 1-ethylimidazole complexes with zinc and cobalt salts of organic and inorganic acids of general formula: wherein R is C 2 H 3 , or C 2 H 5 ; A is Zn(CH 3 COO) 2 ,, Zn(CH 2 COO) 2 ,, Zn(C 6 H 6 O 6 ) or CoCl 2 . Said compounds have ANTIDOTE and antihypoxanthic activities. Bis (1-vinylimidazole) zinc ascorbate improves survival rate of experimental animals when carbon monoxide has acute effect of up to 67%. 1- ethyl imidazole-zinc succinate complex has high protecting activity against acute effect of nitrogen dioxide, reduces the number of experimental animals died of toxic emphysema and increases survival rate up to 75%. 1-ethyl imidazole-zinc acetate complex shows highest protection activity in case of acute hypobaric hypoxia, prolongs survival rate of experimental animals. EFFECT: synthesis of complex substituted imidazole compounds. 5 cl, 7 ex, 3 tbl |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10010584-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2632682-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1383497-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1383497-A2 |
priorityDate | 1995-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.