http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2115646-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f09e8b96fb2be6265df53b4f49836f8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-30 |
filingDate | 1996-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1998-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_619be50ee3989847bb66bfc9ae4d95cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_047cc51cf2605c53b87284a7b24716dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ab685483add2f086b0a1ebde9392f40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ece1f64ac384cf22e301f2ba2944ef1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_876ca18f49ada3426942fb4b01321797 |
publicationDate | 1998-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2115646-C1 |
titleOfInvention | Method of preparing propanol-2 3-substituted 1-amino derivatives |
abstract | FIELD: chemical industry. SUBSTANCE: present invention describes process for preparing propanol-2 3-substituted 1-amino derivatives of general formula: wherein R is H, alkyl or CH 2 CH 2 OH, (CH 2 ) 3 OH, PhCH 2 CH 2 ; R′ is OH, alkoxy, substituted or unsubstituted phenoxy-, amino-, alkylamino- dialkylamino; hydroxyalkylamino; morpholino-, piperidino, piperazino-, substituted or unsubstituted phenylamino-, phenylalkylamino-, -COOH, azido-or SH. The claimed method comprises reacting 1-halogen -2- hydroxypropyl sulphamates of general formula: wherein R is as defined above, M is alkali metal cation, X is Cl or Br, with corresponding nucleophilic reactants at temperatures between 0 and 120 C in water or mixture thereof with aprotic solvent and subsequently treating the resulting 3-substituted 2-hydroxypropyl sulphamates of general formula III: wherein R″=R′ or CN or SNa wherein R, R′, or M are as defined above, with aqueous solutions of mineral acids at temperatures between 80 and 160 C. The method makes it possible to prepare propanol-2 3-substituted 1-amino derivatives with yields of 60 to 90%. Compounds are used as monomers, plasticizers and hardeners of plastic materials, dyes, motor fuel modifiers, biologically active agents, and in organic synthesis. EFFECT: improved properties of the title compounds. 6 ex, 2 tbl |
priorityDate | 1996-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.