| abstract |
FIELD: chemistry of heterocyclic compounds. SUBSTANCE: product: derivatives of methylpiperazine-azepine of the formula (I) given in description where X - O, S, Se, NH or NR 3 where R 3 - , or C 1 -C 4 -alkyl; R 1 , R 2 - H, halogen or C 1 -C 4 -alkyl; N 1 is benzene ring and N 2 is pyridine heterocycle, or vice versus, where nitrogen atom of pyridine ring is at position b, b′,, d or d′ at condition that if R 1 and R 2 are H and X - S, O or NH then N 1 is pyridine ring and N 2 - benzene ring being pyridine nitrogen can not be at position d′; or N 1 and N 2 are both - pyridine rings with nitrogen atom at position b and d′ when X - S and R 1 and R 2 - H, or their salts. Synthesized compounds exhibit activity with respect to central nervous system. EFFECT: improved method of synthesis. 5 cl, 1 tbl |