Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e8da56ea6dccf67262eaf86c56cbfda |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 |
filingDate |
1997-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1998-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c83c8f951ce5b35d336e7753ab40dafd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_300ad2589b14a04c7ca7b3069016ba69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aa411eebe7cdf3d4562d9b3b134eabb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9460c339f6a0a82e9120cc38b1674b13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56032ce38e032b0de5ff6d370081d868 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ab9a8c5f7e8449304e17748d4ec2099 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f0380af8d4ed04f4934015021d654d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5281366a56b5c8e516b9b1c0a18703d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc48a505c06175943df8108ec7031604 |
publicationDate |
1998-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2111962-C1 |
titleOfInvention |
Diethylammonium salt of n-methylamino-1- phenylmethanesulfonic acid having bactericidal activity and chlamydiostatic activity, and method of preparation thereof |
abstract |
FIELD: medical industry. SUBSTANCE: present invention describes diethylammonium salt of N- methylamino-1- phenylmethanesulfonic acid of formula I: . Said compound is prepared by reacting benzylidene methylamine with sulfur dioxide and diethylamine in ethyl alcohol in the presence of 5 mole % triethylbenzylammonium chloride followed by addition of water for 14-16 minutes at 40-50 C. Yield is 91.4+-0.5 %. Empirical formula is C 12 H 22 N 2 O 3 S•. The claimed compound has stable bactericidal and chlamydiostatic activities at concentration in solvent of 10-100 mg/ml directly in vitro and aerosol form at concentration of 1.5-15 mg/l in air. EFFECT: improved properties of the title compound. 2 cl, 5 tbl |
priorityDate |
1997-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |