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filingDate 1997-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1998-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1998-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2111962-C1
titleOfInvention Diethylammonium salt of n-methylamino-1- phenylmethanesulfonic acid having bactericidal activity and chlamydiostatic activity, and method of preparation thereof
abstract FIELD: medical industry. SUBSTANCE: present invention describes diethylammonium salt of N- methylamino-1- phenylmethanesulfonic acid of formula I: . Said compound is prepared by reacting benzylidene methylamine with sulfur dioxide and diethylamine in ethyl alcohol in the presence of 5 mole % triethylbenzylammonium chloride followed by addition of water for 14-16 minutes at 40-50 C. Yield is 91.4+-0.5 %. Empirical formula is C 12 H 22 N 2 O 3 S•. The claimed compound has stable bactericidal and chlamydiostatic activities at concentration in solvent of 10-100 mg/ml directly in vitro and aerosol form at concentration of 1.5-15 mg/l in air. EFFECT: improved properties of the title compound. 2 cl, 5 tbl
priorityDate 1997-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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