| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9618df01b2e29912bf293abb9feb6cce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d1c64fc8f6f030fd7f9cdda1bf26650 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-535 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-535 |
| filingDate |
1991-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1998-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f57e10a61ffca5731a8516a81d090a3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e688baf6bfa981af58a1562d1a2ae80b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08415e9c0984b5d277b4e6eb9b86edc7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4218fbed9573f9c992d61f7d6e6473f |
| publicationDate |
1998-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2108386-C1 |
| titleOfInvention |
Recombinant granulocyte-colony-stimulating factor (g-csf) without additional methionine residue at n-terminus |
| abstract |
FIELD: biotechnology. SUBSTANCE: invention relates to methods of proteins splitting using IgA-proteases, in part, to methods of production of recombinant proteins or polypeptides in procaryotic organisms with possibility the following removal of N-terminal sequence. Recombinant granulocyte-colony-stimulating factor (G-CSF) with additional methionine residue at N-terminus is prepared by splitting the fused protein with IgA-protease. G-CSF is expressed in E. coli cells and this protein has recognition site located between N-terminal methionine and amino acid sequence of G-CSF. EFFECT: improved method of protein splitting. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8951768-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2465328-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9090947-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9163222-B2 |
| priorityDate |
1990-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |