http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2105007-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1271ec4f29a162afb5c66139b1734125 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 |
| filingDate | 1992-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ed6c35dd444c2326d2295546467d48b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b491614bbbcc7b8379353d1aa54e176 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a38768f54669120051353b48baeb73d3 |
| publicationDate | 1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2105007-C1 |
| titleOfInvention | Method of synthesis of benzo-[b]-naphthyridine derivatives and derivatives of benzo-[b]-naphthyridines |
| abstract | FIELD: organic chemistry. SUBSTANCE: invention relates to method of synthesis of derivatives of benzo-[b]-naphthyridine of the general formula (I) where R means carboxyl, (C 1 -C 4 )-alkylhydroxycarbonyl, -CN, carbamoyl, (C 1 -C 4 )-alkylcarbamoyl and di-(C 1 -C 4 )-alkylcarbamoyl; R' - (C 1 -C 4 )-alkyl or (C 3 -C 6 )-cycloalkyl, and their salts. Method involves condensation of chlorofluoroquinoline derivative of the general formula (II) where R 1 - (C 1 -C 4 )-alkyl with amine of the general formula (III): R'-NH-CH 2 -CH 2 -R'' where R'' - (C 1 -C 4 )-alkylhydroxycarbonyl, -CN, carbamoyl, (C 1 -C 4 )-alkylcarbamoyl and di-(C 1 -C 4 )-alkylcarbamoyl. The synthesized derivative of chlorofluoroquinoline is subjected for cyclization followed by oxidation of product and isolation of the end compound as free form or salt. Derivatives of benzo-[b]-naphthyridines of the general formula (I) where R - -CN, carbamoyl, (C 1 -C 4 )-alkylcarbamoyl and di-(C 1 -C 4 )-alkylcarbamoyl are new compounds. EFFECT: improved method of synthesis. 2 cl |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004103991-A1 |
| priorityDate | 1991-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.