abstract |
FIELD: organic chemistry, biochemistry. SUBSTANCE: invention relates to compounds of the general formula (AB) which can be salts or amides and where A means inhibitor of cyclooxygenase having available acid functional group; B means L-form of arginine analogs of the formula: where R 1 ,R 2 and R 3 are different substituents. Invention relates to a method of synthesis of these compounds and their pharmaceutical compositions. EFFECT: improved method of synthesis, enhanced effectiveness of compositions. 8 cl, 8 tbl |