| abstract |
FIELD: organic chemistry. SUBSTANCE: products: derivatives of piperidine of the formula (I) given in description where A and B taken together mean -CH 2 CH 2 -, or A and B taken separately and each means H; X - CH 2 or O; X 1 - H or OH; Z - H, F, Cl or OH; Z 1 - H, F, Cl, Br or C 1 -C 3 -alkyl; n = 0 or 1; m = 0, 1 or 2. Reagent 1: compound of the formula (II) given in description where all substituents have values as indicated for compound (I). Reagent 2: reducing agent, for example NaBH 4 or LiAlH 4 . Reaction conditions: in medium of inert solvent, at (-15)-(+15) C. The synthesized compounds were used in medicine as neuroprotecting agents. EFFECT: improved method of synthesis. 17 cl, 1 tbl |