Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D267-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D267-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D267-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
1992-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1997-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_162932b8d32d087f404988c72a802e5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13b88945d97c674c8a8baaa1baaffcec |
publicationDate |
1997-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2086545-C1 |
titleOfInvention |
Derivatives of dibenz[b,f][1,4]oxazepine-11-on and their pharmaceutically acceptable acid-additive salts, pharmaceutical composition and method for decreasing of multimedicinal resistance of tumor cells against cytotoxic drug |
abstract |
This invention relates to a compound of formula I <CHEM> wherein p is 1 to 3; R<1> and R<2> each are independently hydrogen or an acyl group R<6>CO-, in which R<6> is C1-6 alkyl, C3-7 cycloalkyl, C2-7 alkenyl, aryl or radical of the formula <CHEM> R<3> is hydrogen or chloro; R<4> and R<5> each are independently C1-6 alkyl. Compounds of formula I are useful for the reversal of multidrug resistance of cancer drugs. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2520636-C2 |
priorityDate |
1991-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |