abstract |
FIELD: medicine, more particularly preparation of $$$-bromoisovaleric acid ethyl ester which is substance for preparation of optically inactive cardio agents. SUBSTANCE: claimed process comprises synthesis of isovaleric aldehyde by hydroformylation of isobutene; direct biomination of the resulting aldehyde to $$$- bromoisovaleric acid; etherification of bromoanhydride with ethyl alcohol. EFFECT: more efficient preparation process. 3 tbl |