| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d709e3167fa2f99a1803c9cfeb0aca63 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 |
| filingDate |
1992-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1997-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_febe3f235813fb25abd09b1248aa6d40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15a655456ab8727ff92cb24e992b6b15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acc651854cb61225e826a25f5fcf9945
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b862a093c4f3494603a1b48d7b3989a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97a3bbedc513a3aba9e6356b49412ebc |
| publicationDate |
1997-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2073669-C1 |
| titleOfInvention |
N-imidazolyl-derivatives of the substituted indole, method of their synthesis and pharmaceutical composition |
| abstract |
FIELD: organic chemistry. SUBSTANCE: product: N-imidazolyl-derivatives of the substituted indole of the formula (I) where: p = 1, 2; A - direct C 1 -C 4 -alkylene chain; B - simple bond or direct saturated C 2 -C 4 -hydrocarbon chain; Q - direct or branched saturated C 1 -C 4 -hydrocarbon chain; R 1 and R 2 - H or halogen; R 3 and R 5 - H or C 1 -C 4 -alkyl; R 4 means OR 6 or N(R 6 R 7 ); R 6 and R 7 - H or C 1 -C 4 -alkyl; Reagent 1: compounds of the formula: . Reagent 2: compound of the formula: . Pharmaceutical composition has compound (I) at effective amount and suitable carrier and/or vehicle. Synthesized compounds were used in medicine since they inhibit TxA 2/ -synthase and show activity of antagonist of PGH 2 /TxA 2 -receptors. EFFECT: improved method of synthesis, enhanced effectiveness. 7 cl, 3 tbl |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-000815-B1 |
| priorityDate |
1991-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |